Have you ever closed the door on an opportunity or a relationship in order to open another door, only to realize you made the wrong choice?
I think the closest thing I have come to this is moving back to the USA after one year in Brazil. I was invited to stay another year by the head of my English School and my visa was good for that long. The problem was I missed my friends from college desperately. I didn't even own a computer and calling the US at all was prohibitively expensive. What happened was I moved back and spent six months getting back on my feet financially while most of my friends from school had moved on already. After six months I got hired by Northwest airlines and moved to NYC, but then got laid off 18 months later.
If I had done things differently I might not be a flight attendant at all at this point (which would not be all bad) but I would have left much more fluent in Portuguese and twice as good a Capoeira player and only sacrificed 18 months at a crappy company.